SIGNS Labs, global leader in pheromone research and pheromone technology

Advanced scientific expertise in pheromone research

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SIGNS Labs leverages decades of expertise in animal communication, semiochemistry, and biomimetic innovation to create solutions that enhance adaptive capacity. As the world’s first laboratory fully dedicated to developing pheromone analogue solutions, SIGNS Labs transforms IRSEA’s fundamental research into formulations for both companion animals and livestock.

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Enhancing adaptive capacity through biomimetic innovation

Animals, whether pets or livestock, are continuously exposed to a wide range of environmental, social, and management-related changes. They naturally possess physiological and behavioral mechanisms that allow them to adapt to these everyday variations.

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Novelty is not a problem. Animals remain balanced as long as their adaptive capacities are sufficient to correctly assess situations and respond appropriately. Maintaining this adaptive balance is essential to ensure emotional stability in daily life.

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From early development, maternal pheromones and other natural chemical signals play a key role in shaping emotional security and accurate risk perception. These reassuring signals help animals distinguish harmless situations from genuine threats, allowing them to remain calm and engaged with their environment without unnecessary reactions.

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When these natural reassuring cues are lacking or weakened, animals may gradually lose this adaptive balance. Their ability to cope with routine challenges decreases, making them more vulnerable to overreaction.  

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Secure by SIGNS formulations are designed for daily use, upstream of any imbalance. They support the animal’s natural reassuring signals, helping maintain emotional stability and optimal adaptive capacity over time. By reinforcing calm risk assessment and behavioral flexibility, Secure by SIGNS helps animals face everyday situations serenely.

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From research to proven outcomes

Each product undergoes rigorous scientific validation, including species acceptance, diffusion studies, and stability testing. This ensures that formulations faithfully replicate natural pheromonal signals while effectively promoting emotional balance, behavioral flexibility, and adaptive capacity.

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SIGNS Labs demonstrates that combining scientific research, biomimetic innovation, and practical application can sustainably support animal welfare and improve pet comfort.  This approach prevents behavioral issues caused by the absence of natural chemical cues, instead of just addressing their effects.

From scientific discovery to global reference solutions

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Dr. Patrick Pageat, veterinarian, founder of SIGNS Labs and creator of IRSEA, is a pioneer in animal ethology and chemical communication. His research led to the identification of key maternal pheromone compounds, forming the scientific foundation of Feliway^® and Adaptil^®, developed in partnership with CEVA Santé Animale. These innovations became the world’s first scientifically validated pheromone diffusion solutions for animals.

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Building on this legacy, SIGNS Labs combines patented IRSEA pheromones with its proprietary water-based diffusion technologies to deliver species-specific, safe, and non-invasive solutions. Designed to support emotional stability, adaptive capacity, and animal welfare, SIGNS Labs products embody a commitment to biomimetic innovation, scientific rigor, and global standards in pheromone-based animal care.

SIGNS Labs: patented solutions for animal well-being

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Since 2018, SIGNS Labs has developed its own product lines, leveraging IRSEA patents and using its own proprietary water-based pheromone technology. Solutions contain no toxic ingredients while ensuring safe, controlled, and effective diffusion, translating decades of scientific expertise into high-quality products.

A natural, non-invasive and proven approach to animal welfare

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SIGNS Labs solutions use pheromone analogues to replicate natural chemical signals safely and effectively, helping animals maintain emotional balance and adapt to new or unusual situations.

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Pheromones as safe tools for animal communication

‍Secure by SIGNS products restore semiochemical continuity naturally present during early life. They support adaptation to environmental changes, home adjustments, travel, new companions, or unusual events, promoting emotional stability, security, and harmony.

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Our pheromone-water technology ensures highly effective diffusion and optimal bioavailability, the ability of a substance to be absorbed and assimilated, allowing signals to reach animals efficiently. The water base plays a crucial role in enhancing the availability of active molecules, ensuring they remain detectable by animals rather than binding to surfaces. This results in continuous and consistent delivery when the product is used, making the formula highly effective in supporting animals’ capacity to adapt.

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Rigorous validation through multidisciplinary expertise

SIGNS Labs collaborates closely with Group-IRSEA, veterinarians, ethologists, and behavior specialists. Each formulation is rigorously tested for species acceptance, diffusion efficiency, and stability, ensuring safe, practical, and effective solutions.

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By combining semiochemistry, biomimetic innovation, and practical application,  SIGNS Labs demonstrates how pheromone research and technology can sustainably improve animal welfare, support behavioral flexibility, and enhance well-being and performance for pets and livestock, preventing behavioral difficulties caused by the absence of natural chemical cues.